DNP Insert

Bullet-DNP

Our cryostat inserts polarize substrates using dynamic nuclear polarization (DNP), and enable a rapid-transfer in the solid-state, followed by dissolution with minimal dilution.

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Injection Dock

Injection Dock

Our injection dock loads 5 mm NMR tubes with aqueous solutions in 500 ms. The injection dock is compatible with both conventional dissolution-DNP and bullet-DNP.

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PHIP

Parahydrogen Generator

A low-cost small foot-print para-hydrogen generator for use with liquid nitrogen or helium flow cryostats.

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Bullet-DNP. Fast and scalable dissolution-DNP. Affordable.

Our bullet-DNP systems can be retro-fitted into HyperSense® systems or used in conjunction with cold bore magnets or with readily available flow and bath cryostats.

Bullet-DNP facilitates rapid dissolution of small samples at minimal dilution. Liquid-state 13C polarization levels of 30% have been achieved, with less than 10-fold dilution and only 700 µL of solvent.

See our recent Nature Communications article for further details: DOI.

The inserts are modular, and modules for different nuclei are readily exchanged. Double-resonant versions are under development.

Cernox® sensors and Allen-Bradley sensors to measure temperature and helium level are available, along with affordable controllers.

Sample ejection is fully automated.

Magnetic tunnels to connect the DNP insert to the injection dock are available.

Download the DNP leaflet here.

HyperSense is a registered trademark of Oxford Instruments Molecular Biotools Ltd. Cernox is a registered trademark of Lake Shore Cryotronics, Inc.

DNP Insert - Bottom Part

Injection-Dock. Injection of aqueous and organic solvents within 500 ms.

The injection dock, developed for bullet-DNP, loads aqueous samples into a 3 mm flow NMR tube within less than 500 ms, and achieves a 13C resolution of 3 Hz in a 400 MHz magnet.

It fits into narrow-bore magnets, and features a solvent reservoir with temperature control, and a pneumatically actuated valve that is opened to release the solution into the NMR tube.

The injection dock can stay in the magnet for automatic cleaning.

The injection dock is compatible also with conventional dissolution-DNP. A controller with open source firmware and serial/ethernet interface is available.

Download the DNP leaflet here.

Injection Dock image

Parahydrogen Generator. Low-cost parahydrogen for anyone.

Our low-cost, co-axial parahydrogen generators work with liquid nitrogen as an economic coolant, but can be combined with flow cryostats or cold heads if the highest enrichment of parahydrogen is required. Parahydrogen can be generated continuously at high flow rates, or stored for later use.

  • Pressure Rating: 9 or 13 bar
  • Full Conversion Efficiency at a flow rate of 5 standard litres / minute
  • Swagelok PRV Safety Relief Valve
  • Small Footprint: 30 cm x 40 cm
  • Portable: Weight (with stand) 20 kg

Download the leaflet here.

PHIP Full image